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Dmitriev dima, 5 years, Myelogenous leukemia, the Tyumen Region.

Urgent whip-round of 41 520 USD in order to buy antifungal agent.

At the very beginning of the disease in December 2007 everything shaped by Dima not too well. Leukemia by Dima had such an unusual nature, that doctors couldn’t recognize for 7 month, what the illness of the boy was.

Dima had severe pain syndrome, his bones and articulations were being destroyed. He was treated by surgeons and orthopedists, he was in Russian Ilizarov scientific center for restorative traumatology and orthopaedics in Kurgan, but it had no result, the case became worse and worse. Only in July 2008 Dima got to the first oncological hospital in Ekaterinburg, to a resuscitation department. A powerful anaesthetic therapy was conducted at once, because the 3 years old boy’s strengh was almost over. But even therapy was powerless. The pain won the fight against pain.

The findings of marrow investigation were sent, but doctors could not wait for them and put on high-dose chemotherapy. And they were right in this decision. Their guess was proved. It was myelogenous leukemia. 3 years ago the therapy was efficacious, it got better. The whole course of treatment lasted for 1.5 years.

In August 2009 Dima was discharged from hospital. Doctors were very happy when Dima and his mother visited them in order to get maintenance treatment. The boy became apple-cheeked, curly haired and looked like in good health. But this break was only for half a year and on the 11th of February 2010 Dima got to a resuscitation department of the first oncological hospital in Yekaterinburg again with the same symptoms: pain, vomiting, nausea. And chemotherapy started again. After the first course the marrow cleaned. It’s good for now, but everybody understands that the long courses, long fight for life are yet to come. Remission is the aim. Then it would be possible to start looking for a non-relative donor (the brother was not satisfactory) and to make bone-marrow transplantation.

Now the boy is suffering from infectious complication after chemotherapy. He has a nidus on his right shoulder. It’s so-called fungus or mold. It usually happens by little kids after chemotherapy, when immunity is compromised and every spore from air can develop into a big infection and cause deep wounds.

The doctors used amphotericin B. It weakened the infection but it wasn’t powerful enough to overcome the disease. Amphotericin B is very toxic and it’s not recommended to step up the doses, therefore nontoxic ambisome was extremely needed, but unfortunately it’s unlicensed in Russia. The parents found this medicine in Yekaterinburg, which was left after another child, whom it was already impossible to help. The doctors have ran out of medicine very quick, but it’s necessary to continue the treatment. Moreover it’s necessary to take another antifungal agent at once (cancidas).

Cancidas is available in Russia, ambisome – in Germany. If not for the medicine, dima will be devoured by the infection...

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Urgent whip-round of 41 520 USD in order to buy antifungal agent!

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It’s difficult to add something to this story, especially if you see the photo of the boy and his arm. The photos are horrifying. But it differs just to see the photo and to imagine what the boy has endured. And a very long and complicated treatment lies ahead. The most important thing now is to overcome the infection. The aftertreatment is impossible without it.

The costs of the medicines are huge. Firstly doctors asked to buy cancidas and ampholip. But the last one is toxic. Ambisome is it’s analogue and is more preferable, because ambisome doesn’t have drug pathogenesis. But this drug (ambisome) is not registered in Russia.

We got in touch with a German chemist’s shop. They have this medicine, but the chemist was puzzled by the large quantity we needed for Dima. After we sent Dima's photos, he had no more questions. The medicine is to be picked up only after the whole payment. Cancidas is available in Russia. Please help.

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